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PUBLICATIONS

Mechanism and rationale for inhibition of FASN as a novel therapy for KRAS-mutant non-small cell lung cancer patients

By natalia / 09/2016

Precison: Lung Cancer R&D Summit

DeNovo Palmitate Synthesis Supports Oncogenic Signaling Through Diverse Mechanisms: Implications for FASN-Targeted Therapeutics

By natalia / 08/2016

Journal of Cell Signaling

Preliminary Activity in the First in Human Study of the First-In-Class Fatty Acid Synthase (FASN) Inhibitor, TVB-2640

By Graviton / 06/2016

ASCO Annual Meeting

FASN inhibitor TVB-2640 shows pharmacodynamic effect and evidence of clinical activity in KRAS mutant NSCLC patients in a Phase 1 study

By Graviton / 04/2016

AACR Annual Meeting

Preclinical studies characterize tumor type sensitivity to FASN inhibition and the mechanism and efficacy of novel drug combinations with TVB-2640

By Graviton / 04/2016

AACR Annual Meeting

Preliminary Activity in the First in Human Study of the First-In-Class Fatty Acid Synthase (FASN) Inhibitor, TVB-2640

By Graviton / 03/2016

International Congress on Targeted Anticancer Therapies

Sebum Analysis from Dose Escalation and Expansion Phases of the FASN Inhibitor TVB-2640 Phase 1 Trial, A Non-Invasive Biomarker of Target Engagement

By Graviton / 02/2016

Keystone Symposium – New Frontiers in Understanding Tumor Metabolism

Sebum Analysis from Dose Escalation and Expansion Phases of the FASN Inhibitor TVB-2640 Phase 1 Trial, A Non-Invasive Biomarker of Target Engagement

By Graviton / 02/2016

Keystone Symposium – New Frontiers in Understanding Tumor Metabolism

Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Synctial Virus and Other Respiratory Viruses

By natalia / 12/2015

PLOS ONE

A First in Human Study of the First in Class Fatty Acid Synthase (FASN) Inhibitor TVB-2640. Results of Dose Escalation in Mono and Combination and Evidence of Preliminary Activity

By Graviton / 11/2015

EORTC-NCI-AACR International Conference

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About
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About
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